 | | IU Indianapolis | 58 | | 1-14 |  | | Oakland | 69 | | 10-7 | | Mar 1, 2022 7:00 PM | |  | | Robert Morris | 77 | | 5-14 |  | | Youngstown St. | 73 | | 10-8 | | Mar 1, 2022 7:00 PM | |  | | Green Bay | 62 | | 3-15 |  | | Detroit Mercy | 79 | | 8-7 | | Mar 1, 2022 7:00 PM | |
| | | Oakland | 63 | | 10-7 |  | | Wright St. | 75 | | 12-6 | | Mar 3, 2022 7:00 PM | | | | Detroit Mercy | 59 | | 8-7 |  | | Northern Kentucky | 77 | | 14-4 | | Mar 3, 2022 7:00 PM | |  | | UIC | 72 | | 9-7 |  | | Purdue Fort Wayne | 78 | | 14-5 | | Mar 3, 2022 7:00 PM | | | | Robert Morris | 67 | | 5-14 |  | | Cleveland State | 83 | | 13-6 | | Mar 3, 2022 8:00 PM | |
| | | Wright St. | 82 | | 12-6 | | | Cleveland State | 67 | | 13-6 | | Mar 7, 2022 7:00 PM | | | | Northern Kentucky | 57 | | 14-4 | | | Purdue Fort Wayne | 43 | | 14-5 | | Mar 7, 2022 9:30 PM | |
| | | Wright St. | 72 | | 12-6 | | | Northern Kentucky | 71 | | 14-4 | | Mar 8, 2022 7:00 PM | |
|
